Previous studies have revealed that sites in the cerebral cortex, such as the frontal eye fields and posterior parietal cortex are critical for the proper guidance of head and eye movements. We have begun examining head and eye movements in animals which contain bilateral cooling loops over the superior colliculus and multiple cortical loci. Therefore, in one animal, we are able to assess the contributions of the individual loci as well as in combination with other sites. For example, the frontal eye field can be deactivated unilaterally or bilaterally, combined with another cortical locus or combined with the ipsilateral superior colliculus. These single and multiple deactivations are providing a clearer picture of the sites involved in head and eye movements and how different sites work in concert with each other to produce a single behaviour.